Dear CiPA Community,
On behalf of the CiPA Steering Team, I would like to share some exciting updates.
We are pleased to share materials from the recent May CiPA Update meeting, “The Future of the Assessment of Drug-Induced Arrhythmias and CiPA.” Presentations and a meeting synopsis are now available on the CiPA and CSRC websites. Feel free to share these links with your colleagues!
In addition to the meeting materials, the recommended cardiac ion channel protocols are now available on the CiPA website: http://cipaproject.org/data-resources/. Protocols included are for hERG, CaV1.2 and NaV1.5. As more data is generated, the protocols may evolve and updates will be posted to the website. Should you have any questions, feel free to contact me.
Finally, the Myocyte Pilot Study MEA results were recently published in Toxicological Sciences and are available online ahead of print: http://cipaproject.org/publications/. The study following these results, “Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative,” has been accepted for publication in the open access journal Cell Reports, and an update on the CiPA initiative is now available in Journal for Clinical Studies.
Look forward to regular, quarterly communications or check the CiPA website for more updates soon!
Jennifer Pierson, MPH
Senior Scientific Program Manager
Health and Environmental Sciences Institute (HESI) jpierson@hesiglobal.org